(144) Ruskin, J.; Sachs, R. K.; Wang, M.; Dekeyser, R.; Lew, Z.; Williams, P.; Hwang, H.; Majumdar, A.; Dudding, T.; Lectka, T. "Metal Ion-Induced Large Fragment Deactivation: A Different Strategy for Site-Selectivity in a Complex Molecule" Angew. Chem. Int. Ed. 2023, in press.

(143) Cormanich, R.; Zeoly, L.; Piscelli, B. D. A.; Cariello, G.; Lectka, T. “The Pitfalls of Using JHF Spin-Spin Coupling Constants to Infer Hydrogen Bond Formation in Organofluorine Compounds” Chem. Comm. 2023, in press.

(142) Holt, E.; Ruskin, J.; Garrison, N. G.; Vemulapalli, S.; Lam, W.; Kiame, N.; Henriquez, N.; Borukhova, F.; Williams, J.; Dudding, T.; Lectka, T. “Photoactivated Pyridine Directed Fluorination through Hydrogen Atom Transfer” J. Org. Chem. 2023, in press.

(141) Garrison, N. G.; Harry, S. A.; Siegler, M. A.; Cariello, G.; Cormanich, R. A.; Lectka, T. “The C–F⋅⋅⋅H–CF2 Interaction: A Combination of Hydrogen Bonding and n → σ* Stabilization” J. Fluorine Chem. 2023, 110191.

(140) Wang, M.; Rowshanpour, R.; Guan, L.; Ruskin, J.; Nguyen, P.; Wang, Y.; Zhang, Q.; Liu, R.; Ling, B.; Woltornist, R.; Stephens, A.; Dudding, T.; Lectka, T.; Pitts, C. R. “Competition between C-C and C-H Bond Fluorination: A Continuum of Electron Transfer and Hydrogen Atom Transfer Mechanisms” J. Am. Chem. Soc. 2023, 145, 22442-22455.

(139) Kazim, M.; Feng, Z.; Vemulapalli, S.; Siegler, M. A.; Chopra, A.; Nguyen, P. M.; Holl, M. G.; Guan, L.; Dudding, T.; Tantillo, D. J.; Lectka, T. “Through-Space, Lone-Pair Promoted Aromatic Substitution: A Relay Mechanism Can Beat Out Direct Activation” Chem. Eur. J. 2023, e202301550.

(138) Kazim, M.; Wang, M.; Vemulapalli, S.; Nguyen, P. M.; Wang, Y.; Siegler, M. A.; Dudding, T.; Lectka, T. “How Do Face-to-Face Stacked Aromatic Rings Activate Each Other to Electrophilic Aromatic Substitution?” Org. Lett. 2023, 25, 4318-4322.

(137) Holt, E.; Garrison, N. G.; Rowshanpour, R.; Kim, J. J.; Henriquez, N.; Lam, W.; Kiame, N.; Williams, J.; Zhao, S.; Dudding, T.; Lectka, T. “C-C Bond Activation and Demethylenation of Epoxides by Amine Radical Dications” J. Org. Chem. 2023, 88, 7597-7600.

(136) Wang, M.; Sachs, R. K.; Harry, S. A.; Holt, E.; Siegler, M. A.; Lectka, T. “Bifurcated Hydrogen Bonding to Fluorine in an All cis-Difluoro-Hydroxy Array” J. Fluor. Chem. 2023, 267, e110104.

(135) Holt, E.; Wang, M.; Harry, S. A.; He, C.; Henriquez, N.; Xiang, M. R.; Zhu, A.; Ghorbani, F.; Lectka, T. "An Electrochemical Approach to Directed Fluorination" J. Org. Chem. 2023, 88, 2557-2560.

(134) Harry, S. A.; Garrison, N. G.; Zhu, A.; Xiang, M. R.; Siegler, M. A.; Lectka, T. "C-F Bonds as "Frozen" Nucleophiles: Unconsummated SN2 Reactions" J. Org. Chem. 2022, 87, 13406-13410.

(133) Harry, S. A.; Kazim, M.; Nguyen, P.; Zhu, A.; Xiang, M. R.; Catazaro, J.; Siegler, M.; Lectka, T. "The Close Interaction of a C‐F Bond with an Amide Carbonyl: Crystallographic and Spectroscopic Characterization" Angew. Chem. Int. Ed., 2022, 61, e202207966 (Hot Paper). 

(132) Harry, S. A.; Xiang, M. R.; Holt, E.; Zhu, A. Ghorbani, F.; Patel, P.; Lectka, T. “Hydroxy-Directed Fluorination of Remote Unactivated C(sp3)-H Bonds:  A New Age of Diastereoselective Radical Fluorination” Chem. Sci. 2022, 7007-7013.

(131) Harry, S. A.; Vemulapalli, S.; Dudding, T.; Lectka, T. "Rational Computational Design of Systems Exhibiting Strong Halogen Bonding Involving Fluorine in Bicyclic Diamine Derivatives" J. Org. Chem. 2022, 8413-8419. 

(130) Capilato, J.; Harry, S. A.; Siegler, M.; Lectka, T. “Spectroscopic and Crystallographic Characterization of the R3N+–C–H···X Interaction" Chem. Eur. J. 2022, e2021039.

(129) Dehnen, S.; Schafer, L.; Lectka, T.; Togni, A. "Fluorine: A Very Special Element and Its Very Special Impacts on Chemistry" J. Org. Chem. 2021, 86, 16213-16219.

(128) Hoffmann, K.; Wiesner, A.; Muller, C.; Steinhauer, S.; Beckers, H.; Kazim, M.; Pitts, C. R.; Lectka, T.; Riedel, S. "Structural Proof of a [C-F-C]+ Fluoronium Cation" Nat. Commun. 2021, 12, 5275-5279.

(127) Capilato, J. N.; Lectka, T. "Arene Amination Instead of Fluorination: Substitution Pattern Governs the Reactivity of Dialkoxybenzenes with Selectfluor" J. Org. Chem. 2021, 86, 5771–5777.

(126) Capilato, J. N.; Siegler, M.; Rowshanpour, R.; Dudding, T.; Lectka, T. "Cooperative Noncovalent Interactions Lead to a Highly Diastereoselective Sulfonyl-Directed Fluorination of Steroidal α,β-Unsaturated Hydrazones" J. Org. Chem. 2021, 86, 1300–1307.

(125) Ghorbani, F.; Harry, S. A.; Capilato, J. N.; Pitts, C.; Joram, J.; Peters, G.; Tovar, J.; Smajlagic, I.; Siegler, M.; Dudding, T.; Lectka, T. "Carbonyl-Directed Aliphatic Fluorination: A Special Type of Hydrogen Atom Transfer Beats Out Norrish II" J. Am. Chem. Soc. 2020, 142, 14710–14724.

(124) Smajlagic, I.; Kazim, M.; Lectka, T.; Dudding, T. "DFT Case Study of the Mechanism of a Metal-Free Oxygen Atom Insertion into a p-Quinone Methide C(sp3)–C(sp2) Bond" J. Org. Chem. 2020,  85, 10110-10117. 

(123) Kazim, M.; Guan, L.; Chopra, A.; Sun, R.; Siegler, M. A.; Lectka, T. "Switching a HO···π interaction to a Nonconventional OH···π Hydrogen Bond: A Completed Crystallographic Puzzle" J. Org. Chem. 2020, 85, 9801-9807.  

(122) Kazim, M.; Siegler, M. A.; Lectka, T. "Close Amide NH···F Hydrogen Bonding Interactions in 1,8-Disubstituted Naphthalenes" J. Org. Chem. 2020, 85, 6195-6200. Selected to be Featured in ACS Editors' Choice 

(121) Capilato, J. N.; Pitts, C. R.; Rowshanpour, R.; Dudding, T.; Lectka, T. "Site-Selective Photochemical Fluorination of Ketals: Unanticipated Outcomes in Selectivity and Stability" J. Org. Chem. 2020, 85, 2855-2864.  Published as a selected "Featured Article."

(120) Holl, M. G.; Pitts, C. R.; Lectka, T. "Quest for a Symmetric [C-F-C]+ Fluoronium Ion in Solution: A Winding Path to Ultimate Success" Acc. Chem. Res. 2020, 53, 265-275.

(119) Kazim, M.; Foy, H.; Siegler, M.; Dudding, T.; Lectka, T. "Discovery and Mechanistic Study of a Totally Organic C(aryl)-C(alkyl) Oxygen Insertion Reaction" J. Org. Chem. 2019, 84, 14349-14353. 

(118) York, G.; Siegler, M. A.; Patel, D.; Lectka, T. "Synthesis and X-Ray Crystallography of a Substituted Trityl Fluoride: Ordering Power of a C-F Bond" J. Fluor. Chem. 2019, 228, 109377.

(117) Liu, G.; Ciborowski, S. M.; Pitts, C. R.; Graham, J. D.; Buytendyk, A. M.; Lectka, T.; Bowen, K. H. "Observation of the Dipole- and Quadrupole-Bound Anions of 1,4-Dicyanocyclohexane" Phys. Chem. Chem. Phys. 2019, 18310-18315.

(116) Kazim, M.; Siegler, M. A.; Lectka, T. "A Protonated Quinone Methide Stabilized by a Combination of Partial Aromatization and π-Interaction: Spectroscopic and Crystallographic Analysis" J. Org. Chem. 2019, 84, 8284-8288.

(115) Young, J.; Honick, C.; Zhou, J.; Pitts, C. R.; Ghorbani, F.; Peters, G.; Lectka, T.; Tovar, J. D.; Bragg, A. E. "Energy- and Conformer-Dependent Excited-State Relaxation of an E/Z Photoswitchable Thienyl-Ethene" Phys. Chem. Chem. Phys. 2019, 21, 14440-14452.

(114) Kazim, M.; Siegler, M. A.; Lectka, T. "A Case of Serendipity: Synthesis, Characterization, and Unique Chemistry of a Stable, Ring-Unsubstituted Aliphatic p‑Quinone Methide" Org. Lett. 2019, 21, 2326-2329.

(113) Capilato, J. N.; Bume, D. D.; Lee, W. H.; Hoffenberg, L. E. S.; Jokhai, R. T.; Lectka, T. "Fluorofunctionalization of C=C Bonds with Selectfluor: Synthesis of β-Fluoropiperazines through a Substrate-Guided Reactivity Switch" J. Org. Chem. 2018, 83, 14234-14244.

(112) Bume, D. D.; Harry, S. A.; Lectka, T.; Pitts, C. R. "Catalyzed and Promoted Aliphatic Fluorination" J. Org. Chem. 2018, 83, 8803-8814 (cover art).

(111) Pitts, C. R.; Holl, M. G.; Lectka, T. "Spectroscopic Characterization of a [C-F-C]+ Fluoronium Ion in Solution" Angew. Chem. Int. Ed. 2018, 57, 1924-1927.

(110) Bume, D. D.; Harry, S. A.; Pitts, C. R.; Lectka, T. "Sensitized Aliphatic Fluorination Directed by Terpenoidal Enones: A 'Visible Light' Approach" J. Org. Chem. 2018, 83, 1565-1575.

(109) Holl, M. G.; Pitts, C. R.; Lectka, T. "Fluorine in a C-F Bond as the Key to Cage Formation" Angew. Chem. Int. Ed. 2018, 57, 2758-2766.

(108) Guan, L.; Holl, M. G.; Pitts, C. R.; Struble, M. D.; Siegler, M. A.; Lectka, T. "Through-space Arene Activation Can Override Substituent Effects in Electrophilic Aromatic Substitution" J. Am. Chem. Soc. 2017, 139, 14913-14916.

(107) Bume, D. D.; Pitts, C. R.; Ghorbani, F.; Harry, S. A.; Capilato, J. N.; Siegler, M. A.; Lectka, T. "Ketones as Directing Groups in Photocatalytic sp3 C-H Fluorination" Chem. Sci. 2017, 8, 6918-6923.

(106) Pitts, C. R.; Siegler, M. A.; Lectka, T. "An Intermolecular Aliphatic C-F---H-C Interaction in the Presence of 'Stronger' Hydrogen Bond Acceptors: Crystallographic, Computational, and IR Studies" J. Org. Chem. 2017, 82, 3996-4000.

(105) Pitts, C. R.; Bume, D. D.; Harry, S. A.; Siegler, M. A.; Lectka, T. "Multiple Enone-Directed Reactivity Modes Lead to the Selective Photochemical Fluorination of Polycyclic Terpenoid Derivatives" J. Am. Chem. Soc. 2017, 139, 2208-2211 

(104) Pitts, C. R.; Lectka, T. “Allylic Fluorides” Science of Synthesis Knowledge Updates, 2017.

(103) Struble, M. D.; Guan, L.; Siegler, M. A.; Lectka, T. "A C-F Bond Directed Diels-Alder Reaction" J. Org. Chem. 2016, 81, 8087-8090.

(102) Bume, D. D.; Pitts, C. R.; Jokhai, R. T.; Lectka, T. "Direct, Visible Light-Sensitized Benzylic C-H Fluorination of Peptides using Dibenzosuberenone: Selectivity for Phenylalanine-Like-Residues" Tetrahedron 2016, 72, 6031-6036.

(101) Holl, M. G.; Struble, M. D.; Siegler, M. A.; Lectka, T. "The Close Interaction of a C-F Bond with a Carbonyl π-System: Attractive, Repulsive, or Both?" J. Fluorine Chem. 2016, 188, 126-130.

(100) Pitts, C. R.; Ling, B.; Snyder, J. A.; Bragg, A. E.; Lectka, T. "Aminofluorination of Cyclopropanes: A Multifold Approach through a Common, Catalytically Generated Intermediate" J. Am. Chem. Soc. 2016, 138, 6598-6609.

(99) Holl, M. G.; Struble, M. D.; Singal, P.; Siegler, M. A.; Lectka, T. "Positioning a C-F Bond over the π-Cloud of an Aromatic Ring: A Different Form of Arene Activation" Angew. Chem. Int. Ed. 2016, 55, 8266-8269.

(98) Bume, D. D.; Pitts, C. R.; Lectka T. "Tandem C-C Bond Cleavage of Cyclopropanols and Oxidative Aromatization by Manganese(IV) Oxide in a Direct C-H to C-C Functionalization of Heteroaromatics" Eur. J. Org. Chem. 2016, 16, 26-30.

(97) Keolopile, Z. G.; Gutowski, M.; Buonaugurio, A.; Collins, E.; Zhang, X.; Erb, J.; Lectka, T.; Bowen, K. H.; Allan, M. "Importance of Time Scale and Local Environment in Electron-​Driven Proton Transfer. The Anion of Acetoacetic Acid" J. Am. Chem. Soc. 2015, 137, 14329-14340.   

(96) Struble, M. D.; Holl, M. G.; Scerba, M. T.; Siegler, M. A.; Lectka, T. "Search for a Symmetrical C-F-C Fluoronium Ion in Solution: Kinetic Isotope Effects, Synthetic Labeling, and Computational, Solvent, and Rate Studies" J. Am. Chem. Soc. 2015, 137, 11476-11490.

(95) Pitts, C. R.; Bloom, M. S.; Bume, D. D.; Zhang, Q. A.; Lectka, T. "Unstrained C-C Bond Activation and Directed Fluorination through Photocatalytically-Generated Radical Cations" Chem. Sci. 2015, 6, 5225-5229.

(94) Bloom, S.; Bume, D. D.; Pitts, C. R.; Lectka, T. "Site-Selective Approach to beta-Fluorination: Photocatalyzed Ring Opening of Cyclopropanols" Chem. Eur. J. 2015, 21, 8060-8063.

(93) Struble, M. D.; Holl, M. G.; Coombs, G.; Siegler, M. A.; Lectka, T. "Synthesis of a Tight Intramolecular OH---Olefin Interaction, Probed by IR, 1H NMR, and Quantum Chemistry" J. Org. Chem. 2015, 80, 4803-4807.

(92) Preimesberger, M. R.; Majumdar, A.; Aksel, T.; Sforza, K.; Lectka, T.; Barrick, D.; Lecomte, J. T. J. "Direct NMR Detection of Bifurcated Hydrogen Bonding in the α-​Helix N-​Caps of Ankyrin Repeat Proteins" J. Am. Chem. Soc. 2015, 137, 1008-1011.

(91) Bloom, S.; McCann, M.; Lectka, T. "Photocatalyzed Benzylic  Fluorination: Shedding “Light” on the Involvement of Electron Transfer" Org. Lett. 2014, 16, 6338-6341.

(90) Griswold, A.; Bloom, S.; Lectka, T. "A Chelating Nucleophile Plays a Starring Role: 1,8-Naphthyridine- Catalyzed Polycomponent a,a-Difluorination of Acid Chlorides" J. Org. Chem. 2014, 79, 9830-9834.

(89) Pitts, C. R.; Ling, B.; Woltornist, R.; Liu, R.; Lectka, T. "Triethylborane-Initiated Radical Chain Fluorination: A Synthetic Method Derived from Mechanistic Insight" J. Org. Chem. 2014,79, 8895-8899.

(88) Bloom, S.; Knippel, J. L.; Holl, M. G.; Barber, R.; Lectka, T. "A Cooperative Allylic Fluorination: Combination of Nucleophilic and Electrophilic Fluorine Sources" Tetrahedron Lett. 2014, 55, 4576-4580.

(87) Struble, M. D.; Kelly, C.; Siegler, M. A.; Lectka, T. (Chosen as VIP [Very Important Paper]) "Search for a Strong, Virtually "No-Shift" Hydrogen Bond: A Cage Molecule  with an Exceptional OH···F Interaction" Angew. Chem. Int. Ed. 2014, 53, 8924-8928.

(86) Pitts, C. R.; Bloom, S.; Woltornist, R.; Auvenshine, D. J.; Ryzhkov, L. R.; Siegler, M. A.; Lectka, T. "Direct, Catalytic Monofluorination of sp3 C-H Bonds: A Radical-Based Mechanism with Ionic Selectivity" J. Am. Chem. Soc. 2014, 136, 9780-9791.

(85) Pitts, C. R.; Lectka, T. "Chemical Synthesis of β-Lactams: Asymmetric Catalysis and Other Recent Advances" Chem. Rev. 2014, 7930-7953.

(84) Struble, M. D.; Strull, J.; Patel, K.; Siegler, M. A.; Lectka, T. (Featured article and cover art) "Modulating 'Jousting' C−F---H−C Interactions with a Bit of Hydrogen Bonding" J. Org. Chem. 2014, 79 (1), 1–6.

(83) Bloom, S.; Knippel, J. L.; Lectka, T. "A Photocatalyzed Aliphatic Fluorination" Chem. Sci. 2014, 5, 1175-1178.

(82) Bloom, S.; Sharber, S. A.; Holl, M. G.; Knippel, J. L.; Lectka, T. "Metal-Catalyzed Benzylic Fluorination  as Synthetic Equivalent to 1,4-Conjugate Addition of Fluoride" J. Org. Chem. 2013, 78 (21), 11082–11086.

(81) DeBlase, A. F.; Bloom, S.; Lectka, T.; Jordan, K. D.; McCoy, A. B.; Johnson, M. A. "Origin of the Diffuse Vibrational Signature of a Cyclic Intramolecular Proton Bond: Anharmoni Analysis of Protonated 1,8- Disubstituted Naphthalene Ions" J. Chem. Phys. 2013, 139, 024301.

(80) DeBlase, A. F.; Scerba, M. T.; Lectka, T.; Johnson, M. A. "Vibrational Predissociation Spectroscopy of Ar- Tagged, Trisubstituted Silyl Cations" Chem. Phys. Lett. 2013,568-569, 9-13.

(79)  Struble, M. D.; Scerba, M. T.; Siegler, M.; Lectka, T. "Evidence for a Symmetrical Fluoronium Ion in Solution" Science 2013, 340, 57-60.

(78) Bloom, S.; Pitts, C. R.; Woltornist, R.; Griswold, A.; Holl, M. G.; Lectka, T. "Iron(II)-Catalyzed Benzylic Fluorination" Org. Lett. 2013, 15, 1722-1724.

(77) Bloom, S.; Pitts, C. R.; Miller, D.; Haselton, N.; Holl, M. G.; Urheim, E.; Lectka, T.  "A Polycomponent  Metal- Catalyzed Aliphatic, Allylic, and Benzylic Fluorination" Angew. Chem. 2012, 51, 10580-10583.

(76) Erb, J.; Strull, J.; Miller, D.; He, J.; Lectka, T. "The Diels–Alder Cyclization of Ketenimines" Org. Lett. 2012, 14(8), 2191-2193.

(75) Scerba, M. T.; DeBlase, A. F.; Bloom, S.; Dudding, T.; Johnson, M. A.; Lectka, T. "Characterization  of Highly Unusual NH+–O Hydrogen Bonding to Ester Ether Oxygen Atoms through Spectroscopic and Computational Studies" J. Phys. Chem. 2012, 116, 3556-3560.

(74) Scerba, M. T.; Bloom, S.; Haselton, N.; Siegler, M. A.; Jaffe, J. Bair, N.; Lectka, T. "Interaction  of a C-F Bond with the π-System of a C=C Bond or ‘Head On’ with a Proximate C-H Bond” J. Org. Chem. 2012, 77, 1605-1609.

(73) Scerba, M. T.; Leavitt, C. M.; Diener, M. E.; Deblase, A. F.; Guasco, T. L.; Siegler, M. A.; Bair, N.; Johnson, M. A.; Lectka, T. "NH+-F Hydrogen Bonding in a Fluorinated "Proton Sponge" Derivative: Integration of Solution, Solid-State, Gas-Phase, and Computational Studies" J. Org. Chem. 2011, 76, 7975-7984.

(72) Scerba, M. T.; Leavitt, C. M.; Diener, M. E.; Deblase, A. F.; Guasco, T. L.; Siegler, M. A.; Bair, N.; Johnson, M. A.; Lectka, T. "NH+-F Hydrogen Bonding in a Fluorinated "Proton Sponge" Derivative: Integration  of Solution, Solid-State, Gas-Phase, and Computational Studies" J. Org. Chem. 2011, 76, 7975-7984.

(71) Bloom, S.; Scerba, M. T.; Erb, J.; Lectka, T. "Tricomponent Catalytic a,a-Difluorination of Acid Chlorides" Org. Lett. 2011, 13, 5068-5071.

(70) Erb, J.; Paull, D. H.; Belding, L.; Dudding, T.; Lectka, T. "From Bifunctional  to Trifunctional  (Tricomponent Nucleophile–Transition Metal–Lewis Acid) Catalysis: The Catalytic, Enantioselective a-Fluorination of Acid Chlorides" J. Am. Chem. Soc. 2011, 133, 7536-7546.

(69) “Combining Asymmetric  Catalysis with Natural Product Functionalization through Enantioselective a- Fluorination” Erb. J.; Alden-Danforth, E.; Kopf, N.; Scerba, M. T.; Lectka, T. J. Org. Chem. 2010, 75, 969-971.

(68) "Catalytic, Asymmetric  Reactions of Ketenes and Ketene Enolates" Paull, D. H.; Weatherwax,  A.; Lectka, T. Tetrahedron 2009, 65, 6771-6803.

(67) "Diastereoselective Synthesis of trans-b-Lactams Using a Simple Multifunctional Catalyst " Abraham, C.; Paull, D.; Dogo-Isonagie, C.; Lectka, T. Synlett 2009, 10, 1651-1654.

(66) "Catalytic, Asymmetric a-Fluorination of Acid Chlorides: Dual Metal-Ketene Enolate Activation" Paull, D. H.; Scerba, M. T.; Alden-Danforth, E.; Widger, L. R.; Lectka, T. J. Am. Chem. Soc. 2008, 130, 17260-17261.

(65) "A Surprising Mechanistic "Switch" in Lewis Acid Activation: A Bifunctional,Asymmetric Approach to alpha-Hydroxy Acid Derivatives" Abraham, C. J.; Paull, D. H.; Bekele, T.; Scerba, M. T.; Dudding, T; Lectka, T. J. Am. Chem. Soc. 2008, 130, 17085-17094.

(64) "Asymmetric Cycloadditions of o-Quinone Methides Employing Chiral Ammonium Fluoride Catalysts" Alden-Danforth, E.; Scerba, M. T.; Lectka, T. Org. Lett. 2008, 10, 4951-4953.

(63) "Mechanistic Insights into the Inhibition of Prostate Specific Antigen by b-Lactam Class Compounds" Singh, P.; Williams, S. A.; Shah, M. H.; Lectka, T., Pritchard, G. J.; Isaacs, J. T.; Denmeade, S. R. Proteins-Structure Function and Bioinformatics 2008, 70, 1416-1428.

(62) "Bifunctional Asymmetric Catalysis: Cooperative Lewis Acid-Base Systems" Paull, D. H.; Abraham,  C. J.; Scerba, M. T.; Alden-Danforth, E.; Lectka, T. Acc. Chem. Res. 2008, 41, 655-663.

(61) “Catalytic, Asymmetric Inverse Electron Demand Hetero Diels-Alder Reactions of o-Benzoquinone Derivatives and Ketene Enolates” Paull, D. H.; Wolfer, J.; Grebinski, J. W.; Weatherwax, A.; Lectka, T. Chimia 2007, 61, 240-246.

(60) “An Asymmetric, Bifunctional Catalytic Approach to Non-Natural a-Amino Acid Derivatives” Paull, D. H.; Alden-Danforth, E.; Dogo-Isonagie, C.; Abraham, C. J.; Wolfer, J. J. Org. Chem.  2007, 72, 5380-5382.

(59) "A Mechanistic Study on the Catalytic, Asymmetric a-Bromination of Acid Chlorides" Dogo-Isonagie, C.; Bekele, T.; France, S.; Wolfer, J.; Weatherwax, A.; Taggi, A. E.; Paull, D. H.; Dudding, T.; Lectka, T. Eur. J. Org. Chem. 2007, 7, 1091-1100.

(58) "Scalable Methodology for the Catalytic, Asymmetric a-Bromination of Acid Chlorides" Dogo-Isonagie, C.; Bekele, T.; France, S.; Wolfer, J.; Weatherwax, A.; Taggi, A. E.; Lectka, T. J. Org. Chem.   2006, 71, 8946-8949.

(57) "Catalytic, Enantioselective Bifunctional Inverse Electron Demand Hetero-Diels-Alder Reactions of Ketene Enolates and o-Benzoquinone Diimides" Abraham, C. J.; Paull, D. H.; Scerba, M. T.; Grebinski, J. W.; Lectka, T. J. Am. Chem. Soc. 2006, 128, 13370-13371.

(56) "Catalytic, Asymmetric Synthesis of 1,4-Benzoxazinones: A Remarkably Enantioselective Route to α-Amino Acid Derivatives from o-Benzoquinone Imides" Wolfer, J.; Bekele, T.; Abraham, C. J.; Dogo-Isonagie, C.; Lectka, T. Angew. Chem. 2006, 45, 7398-7400.

(55) "Catalytic, Enantioselective [4+2]-Cycloadditions of Ketene Enolates and o-Quinones: Efficient Entry to Chiral, α-Oxygenated Carboxylic Acid Derivatives” Bekele, T.; Wolfer, J.; Abraham, C.; Shah, M. H.; Weatherwax, A.; Lectka, T. J. Am. Chem. Soc.2006, 128, 1810-1811.

(54)  "Bifunctional Lewis Acid-Nucleophile Based Asymmetric Catalysis: Mechanistic Evidence for Imine Activation Working in Tandem with Chiral Enolate Formation in the Synthesis of β-Lactams” France, S.; Shah, M. H.; Weatherwax, A.; Wack, H.; Roth, J. P.; Lectka, T. J. Am. Chem. Soc.2005, 127, 1206-1216.

(53) “A Column-Based ‘Flush and Flow’ System for the Asymmetric a-Chlorination of Acid Halides” Bernstein, D.; France, S.; Wolfer, J.; Lectka, T. Tetrahedron Asymmetry 2005, 16, 3481-3483.

(52) “An Anionic Nucleophilic Catalyst System for the Diastereoselective Synthesis of trans-β−Lactams” Weatherwax, A.; Abraham, C. J.; Lectka, T. Org. Lett. 2005, 7, 3461-3463.

(51) “Performing the Synthesis of a Complex Molecule on Sequentially Linked Columns: Toward the Development  of a ‘Synthesis Machine’” France, S.; Bernstein, D.; Weatherwax, A.; Lectka, T. Org. Lett. 2005, 7, 3009-3012.

(50) "Recent Developments  in Catalytic, Asymmetric a-Halogenation: A New Frontier in Asymmetric  Catalysis" France, S.; Weatherwax, A.; Lectka, T. Eur. J. Org. Chem. 2004, 3, 475-479.

(49) "Development of a New Dimeric Cyclophane Ligand: Application  to Enhanced Diastereo- and Enantioselectivity  in the Catalytic Synthesis of b-Lactams" Wack, H.; France, S.; Hafez, A. M.; Drury, W. J., III; Weatherwax, A.; Lectka, T. J. Org. Chem. 2004, 69, 4531-4533.

(48) “Advances in the Catalytic, Asymmetric Synthesis of b-Lactams” France, S.; Weatherwax, A.;  Taggi, A. E.; Lectka, T. Acc. Chem. Res. 2004, 37, 592-600.

(47) “Catalytic, Asymmetric  a-Chlorination of Acid Halides” France, S.; Wack, H.; Taggi, A. E.; Hafez, A. M.; Wagerle, T. R.; Shah, M. H.; Dusich, C. L.; Lectka, T. J. Am. Chem. Soc. 2004, 126, 4245-4255.

(46)  “Bicarbonate  Salts  asCost-Effective Bases for the Synthesis of Ketenes and Their Synthetic Equivalents Applied to the Asymmetric  Synthesis of b-Lactams” Shah, M. H.; France, S. F.; Lectka, T. Synlett 2003, 12, 1937-1939. 

(45) "Imino Esters as Versatile Precursors for Enantioselective Amino Acid Synthesis" Taggi, A. E.; Hafez, A. M.; Lectka, T. Acc. Chem. Res. 2003, 36, 10-19.

(44) "A Multistage, One-Pot Procedure Mediated by a Single Catalyst: A New Approach to the Catalytic Asymmetric  Synthesis of Amino Acids" Hafez, A. M.; Dudding, T.; Wagerle, T. R.; Shah, M. H.; Taggi, A. E.; Lectka, T. J. Org. Chem. 2003, 68, 5819-5825.

(43) “Nucleophilic Chiral Amines as Catalysts in Asymmetric  Synthesis” France, S. F.; Guerin, D. J.; Miller, S. J.; Lectka, T. Chem. Rev. 2003, 103, 2985-3012.

(42) "Molecular Mechanics Calculations as Predictors of Enantioselectivity for Chiral Nucleophile Catalyzed Reactions" Taggi, A. E.; Hafez, A. M.; Dudding, T.; Lectka, T. Tetrahedron 2002, 58, 8351-8356.

(41) "Sequential Column Asymmetric Catalysis (CAC)" Hafez, A. M.; Taggi, A. E.; Lectka, T. Chemistry Eur. J. 2002, 8, 4114-4119 (invited contribution).

(40) "Bifunctional Asymmetric Catalysis: A Tandem Nucleophile-Lewis Acid Promoted Synthesis of β-Lactams" France, S.; Wack, H.; Hafez, A. M.; Taggi, A. E.; Witsil, D.; Lectka, T. Org. Lett. 2002, 4, 1603-1605.

(39) "The Development of the First Catalyzed Reaction of Ketenes and Imines: Catalytic, Asymmetric Synthesis of b-Lactams" Taggi, A. E.; Hafez, A. H; Wack, H.; Young, B.; Ferraris, D.; Lectka, T. J. Am. Chem. Soc. 2002, 124, 6626-6635.

(38) "Catalysts that Play Multiple Roles: Asymmetric Synthesis of b-Amino Acid Derivatives through a Four- Stage, One-Pot Procedure" Dudding, T.; Hafez, A. M.; Taggi, A. E.; Lectka, T. Org. Lett. 2002, 4, 387-390.

(37) "Generation of Ketenes Using NaH-Crown Ether Shuttle-Deprotonation for Use In Asymmetric  Catalysis" Taggi, A. E.; Wack, H.; Hafez, A. M.; France, S.; Lectka, T. Org. Lett. 2002, 4, 627-629.

(36) "Catalytic, Enantioselective Alkylation of a-Imino Esters: The Synthesis of Nonnatural α-Amino Acid Derivatives" Ferraris, D.; Young, B.; Dudding, T.; Cox, C.; Drury, W.  J. III; Lectka, T. J. Am. Chem. Soc. 2002, 124, 67-77.

(35) "Asymmetric  Catalysis on Sequentially-Linked  Columns" Hafez, A. M.; Taggi, A. E.; Dudding, T.; Lectka, T. J. Am. Chem. Soc. 2001, 123, 10853-10859 (C&E News Profile).

(34) "Reactive Ketenes through a Carbonate-Amine Shuttle Deprotonation Strategy: Catalytic, Enantioselective a-Bromination of Acid Chlorides"  Hafez, A. M.; Wack, H.; Taggi, A. E. Esterbrook, J.; Lectka, T. Org. Lett. 2001, 3, 2049-2051.

(33) "Catalytic, Asymmetric a-Halogenation" Wack, H.; Hafez, A. M.; Taggi, A. E; Drury,  W. J. III; Lectka, T. J. Am. Chem. Soc. 2001, 123, 1531-1532.

(32) "Column Asymmetric Catalysis for b-Lactam Synthesis" Hafez, A. M.; Taggi, A. E.; Wack, H.; Lectka, T. Org. Lett. 2000, 2, 3963-3965.

(31) "Catalytic, Asymmetric Synthesis of b-Lactams" Taggi, A. E.; Hafez, A. M.; Wack, H.; Lectka, T. J. Am. Chem. Soc. 2000, 122, 7831-7832.

(30) "Synthetic Catalysis of Amide Isomerization" Cox, C.; Lectka, T. Acc. Chem. Res. 2000, 33, 849-858.

(29) "Nucleophilic  Metal Complexes as Acylation Catalysts: Solvent-Dependent  'Switch' Mechanisms  Leading to the First Catalyzed Staudinger  Reaction" Wack, H.; Drury, W. J. III; Taggi, A. E.; Ferraris, D.; Lectka, T. Org. Lett. 1999, 1, 1985-1988.

(28) "Nucleophilic Catalysis of Amide Isomerization" Cox, C.; Wack, H.; Lectka, T. J. Am. Chem. Soc. 1999, 121, 7963-7964.

(27) "Intramolecular Acid-Catalyzed Amide Isomerization in Aqueous Solution" Cox, C.; Lectka, T. Org. Lett. 1999, 1, 749-752.

(26) "Enantioselective  Alkylations of N,O-Acetals" Ferraris, D.; Dudding, T.; Young, B.; Drury, W. J. III; Lectka, T. Tetrahedron 1999, 55, 8869-8882.

(25) "Catalytic, Enantioselective Alkylations of N,O-Acetals" Ferraris, D.; Dudding, T.; Young, B.; Drury, W. J. III; Lectka, T. J. Org. Chem. 1999, 64, 2168-2169.

(24) "Strong Hydrogen Bonding to an Amide Nitrogen in an 'Amide Proton Sponge': Consequences  for Structure and Reactivity" Cox, C.; Wack, H.; Lectka, T. Angew. Chem. 1999, 111, 798-799.

(23) "A Novel Synthesis of α-Amino Acids through Catalytic, Enantioselective Ene Reactions of α-Imino  Esters" Drury, W. J. III; Ferraris, D.; Cox, C.; Young, B.; Lectka, T. J. Am. Chem. Soc. 1998, 120, 11006-11007.

(22) "Diastereo- and Enantioselective Alkylation of a-Imino Esters with Cyclic Enol Silanes Catalyzed by (R)-Tol- BINAP-CuClO4•(MeCN)2" Ferraris, D.; Young,  B.; Cox, C.; Drury,  W. J. III; Dudding, T.; Lectka, T. J. Org. Chem. 1998, 63, 6090-6091.

(21) "Intramolecular Catalysis of Amide Isomerization: The 5-N-H--Na  Interaction in Prolyl Peptides" Cox, C.; Lectka, T. J. Am. Chem. Soc. 1998, 120, 10660-10668.

(20) "'Orthogonal' Lewis Acids: Catalyzed Ring Opening and Rearrangement of Acyl Aziridines" Ferraris, D.; Drury, W. J. III; Cox, C.; Lectka, T. J. Org. Chem. 1998, 63, 4568-4569.

(19) "Catalytic, Enantioselective Alkylation of a-Imino Esters Using Late Transition Metal Phosphine Complexes as Catalysts" Ferraris, D.; Young, B.; Dudding, T.; Lectka, T. J. Am. Chem. Soc. 1998, 120, 4548-4549.

(18) "Solvent Effects on Carbamate Isomerization" Cox, C.; Lectka, T. J. Org. Chem. 1998, 63, 2426-2427.

(17) "C-F Bond Activation by Aryl Carbocations: Conclusive Intramolecular Fluoride Shifts Between Carbon Atoms in Solution and the First Examples of Intermolecular Fluoride Ion Abstractions" Ferraris, D.; Cox, C.; Anand, R.; Lectka, T. J. Am. Chem. Soc. 1997, 119, 4319-4320.

(16) "Intramolecular Catalysis of Amide Isomerization" Cox, C.; Young, Jr. V. G.; Lectka, T. J. Am. Chem. Soc. 1997, 119, 2307-2308.

(15) "Copper(II)-Catalyzed Amide Isomerization: Evidence for N-Coordination" Cox, C.; Ferraris, D.; Murthy, N. N.; Lectka, T. J. Am. Chem. Soc. 1996, 118, 5332-5333.

(14) Lectka, T. Active Metals Fürstner, A. ed. VCH, Weinheim, 1996, p. 85.

(13) Stone, M. B.; Rittner, J.; Chen, Y.; Yardimci, H.; Reich, D. H.; Broholm, C.; Ferraris, D. V.; Lectka, T. "Cu2(1,4- diazacycloheptane)2Cl4 is not a Spin Ladder" Los Alamos National Laboratories Condensed Matt. 2001, 1-11.

(12) Stone, M. B.; Chen, Y.; Rittner, J.;. Yardimci, H.; Reich, D. H.; Broholm, C.; Ferraris, D. V.; Lectka T. "Frustrated Three-Dimensional Quantum Spin Liquid in CuHpCl" Physical Review B 2002, 65, 64423-64430.

(11) Lectka, T. "Industry-University Compromise" Chemical and Engineering News, March 26, 2001, p. 269.

(10) Chiral Bis(oxazoline)copper(II) Complexes as  Lewis Acid Catalysts for the Enantioselective Diels-Alder Reaction" Evans, D. A.; Miller, S. J.; Lectka, T.; von Matt, P. J. Am. Chem. Soc. 1999, 121, 7559-7573.

(9)  "Bis(oxazoline) and Bis(oxazolinyl)pyridine Copper Complexes as Enantioselective Diels-Alder Catalysts. Reaction Scope and Synthetic Applications" Evans, D. A.; Barnes, D. M.; Johnson, J. S.; Lectka, T.; von Matt, P.; Miller, S. J.; Murry, J. A.; Norcross, R. D.; Shaughnessy, E. A.; Campos, K. R. J. Am. Chem. Soc. 1999, 121, 7582-7594.

(8) "Carbocations with Bent Three-Center, Two-Electron  C-H-C Bonds" McMurry, J. E.; Lectka,  T. J. Am. Chem. Soc. 1993, 115, 10167-10173.

(7) "Bis(imine)-Copper(II) Complexes as Chiral Lewis Acid Catalysts  in the Diels-Alder  Reaction"  Evans, D. A.; Lectka, T.; Miller, S. J. Tetrahedron Lett. 1993, 34, 7027-7030.

(6) "Bis(oxazoline)-Copper(II) Complexes as Chiral Catalysts for the Enantioselective Diels-Alder Reaction" Evans, D. A.; Miller, S. J.; Lectka, T. J. Am. Chem. Soc. 1993, 115, 6460-6461.

(5)  "Three-Center, Two-Electron C-H-C Bonds in Organic  Chemistry" McMurry, J. E.; Lectka, T. Acc. Chem. Res. 1992, 25, 47-53.

(4) "A Remarkable Alkane Protonolysis Reaction: Observation of Stoichiometric Hydrogen Formation" McMurry, J. E.; Lectka, T. J. Am. Chem. Soc. 1990, 112, 869-870.

(3) "The in-Bicyclo[4.4.4]-1-tetradecyl Cation: A Stable Substance with a Three-Center, Two-Electron C-H-C Bond" McMurry, J. E.; Lectka, T.; Hodge, C. N. J. Am. Chem. Soc. 1989, 111, 8867-8872.

(2) "An Optimized Procedure for Titanium-Induced Carbonyl  Coupling"  McMurry, J. E.; Lectka, T.; Rico, J. G.J. Org. Chem. 1989, 54, 3748-3749.

(1) "Intramolecular  Reactions of 2-Acyl-4-oxa-1,5-hexadienes" Matlin, A. R.; Lectka, T.; McGarvey, D. J.; Jacob, P. W.;  Picken, H. A. Tetrahedron Lett. 1987, 28, 5083-5086.